top of page
PangramSansMedium.png

Featured News

"The Startup Selection 2026: The Companies Thinking Beyond the Mainstream"

The Marker. (2026)

Read More
"Can adding light sensors to nerve cells switch off pain, epilepsy, and other disorders?"

Science. (2025)

Read More
"Modulight Biotherapeutics announces $12 million seed funding for novel optogenic therapy to treat neurological disorders"

PR Newswire. (2025)

Read More
"Light Medicine: How the Flip of a Switch Could Replace Surgery, Medication and Hospitalization"

Haaretz. (2025)

Read More
"Novel OptoGPCRs open new avenues in optogenetic modulation"

SPIE Photonics West Daily. (2025)

Read More

Publications

Foundational Science:
GPCR Opsin Development
"Efficient optogenetic silencing of neurotransmitter release with a mosquito rhodopsin"

Mahn, M., Saraf-Sinik, I., Patil, P., … Lüthi, A., Rost, B.R., Wiegert, J.S. & Yizhar O. 

Neuron. 109, 10, p. 1621-1635.e8, (2021) 

Read More
"Optogenetics at the Presynapse"

Rost, B.R., Wietek, J., Yizhar, O. & Schmitz, D. 

Nature Neuroscience. 25, 8, p. 984-998, (2025)

Read More
Preclinical studies and Translational Research
"Roadmap for direct and indirect translation of optogenetics into discoveries and therapies for humans"

Luscher C., Emiliani V., Farahany N., Gittis A., Gradinaru V., High K.A., Roska B., Sahel J-A., Yizhar O., Zeng H. & Deisseroth K.

Nature Neuroscience Abstract #28, pg 2415–2431 (2025)

Read More
"Exploring GPCR-mediated optogenetic modulation of seizure network in a pig model of Temporal Lobe Epilepsy"

Chang, S., Bar-Or, K.L., Mivalt, F., Maltais, D., Kfir, Y., Kim, J., Kim, I., Hershko, M., Daily, J., Swissa, E., Levi, O., Devore, S., Yizhar, O., Eldar, Y., & Worrell, G. 

bioRxiv, (2025)

Read More
"Towards clinical translation of optogenetic seizure inhibition"

Swissa, E., Bar,-Or K.L., Auerbach-Asch, C.R., Kfir, Y., Yizhar, O., Levi, O., Eldar, Y. 

Society for Neuroscience Annual Meeting, Abstract #026.53, (2024)

Read More
Basic Research using eOPN3
Group 20.png
bottom of page